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8-K ·Filed Aug 28, 2026

APRE

Aprea Therapeutics, Inc.
NEUTRAL
Impact 2/10
Horizonmonths Processed1mo ago SEC0001104659-26-102795
8-K context-dependent: Items 8.01
Actionable Insight • Neutral

This is a routine IP portfolio update with no trading implications. Monitor upcoming clinical data readouts for APR-1051 (ACESOT-1051 Phase 1) and any potential combination development for ATRN-119 for material catalysts.

DirectionNeutral
Confidencehigh
Horizonmonths
Latest settled — T+20d
APRE ▼ -10.35% at T+20d
NEUTRAL call -10.35% · α vs SPY -10.61% · entry $0.8386 → $0.7518
Next anchor: T+60d in 28d
Latest observation: T+39 -43.06% FF3 residual α
Entry = T+0 close
Aug 28, 2026
via day close
T+1d
-4.60%
call -4.60% · α -4.30%
$0.8000
settled 8w ago
T+5d
-5.28%
call -5.28% · α -5.39%
$0.7943
settled 7w ago
T+20d
-10.35%
call -10.35% · α -10.61%
$0.7518
settled 28d ago
T+60d
Pending
in 28d

Price Chart

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Executive Summary

Aprea Therapeutics issued a press release on August 28, 2026, announcing an expansion of its intellectual property portfolio for its precision oncology programs. The filing is a routine update on patent counts and expiration dates for its WEE1 and ATR inhibitor programs, providing no new financial data, clinical results, or material changes to the business. This is a non-material, administrative update with no immediate impact on the stock.

Key Facts

  • Aprea announced an update to its global intellectual property portfolio, reporting 28 issued and 30 pending patents.
  • The WEE1 inhibitor program (APR-1051) has 2 pending U.S. applications, 1 pending U.S. provisional, 2 granted non-U.S. patents, and 12 pending non-U.S. applications; if granted, will expire in 2047.
  • The ATR inhibitor program (ATRN-119) has 4 granted U.S. patents, 1 pending U.S. application, 22 granted non-U.S. patents, and 13 pending non-U.S. applications; granted patents expire 2035-2037, pending could extend to 2045.
  • No financial figures, clinical data, or guidance were provided in the filing.

Financial Impact

No financial impact disclosed or estimable from this filing.

Risk Factors

  • No new financial or operational risks disclosed in this filing.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
90% bullish (10 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001104659-26-102795
Document: 0001104659-26-102795-index.html0001104659-26-102795
Document: 0001104659-26-102795.txt0001104659-26-102795
12 reports for APRE
Performance horizon
50% Hit rate @ T+60 3 of 6 directional calls Went positive at some point 6 of 6 best @ T+60▲ +24.32%Apr 22, 2026
Filters
Rows
Reports for APRE — sortable, filterable
TypeNow
Aug 28, 2026
8w ago
8-K
NEUTRAL ★ 2/10
$0.8386awaiting T+60—$0.5180 (−38.23%)
Aug 12, 2026
10w ago
8-K
NEUTRAL ★ 5/10
$0.6830awaiting T+60—$0.5180 (−24.16%)
Aug 12, 2026
10w ago
Press Release
NEUTRAL ★ 5/10
$0.6830awaiting T+60—$0.5180 (−24.16%)
May 13, 2026
23w ago
8-K
BULLISH ★ 7/10
$0.8800 $0.6503▼ −26.10%▼ −30.54%$0.5180 (−41.14%)
May 13, 2026
23w ago
Press Release
NEUTRAL ★ 5/10
$0.8800 $0.6503▼ −26.10%▼ −30.54%$0.5180 (−41.14%)
Apr 30, 2026
25w ago
DEFA14A
BEARISH ★ 7/10
$0.8000 $0.6247▲ +21.91%▲ +25.02%$0.5180 (+35.25%)
Apr 22, 2026
26w ago
S-3
BEARISH ★ 7/10
$0.8840 $0.6690▲ +24.32%▲ +29.34%$0.5180 (+41.40%)
Apr 21, 2026
26w ago
Press Release
BULLISH ★ 7/10
$0.9070 $0.6900▼ −23.93%▼ −30.82%$0.5180 (−42.89%)
Mar 31, 2026
29w ago
Insider Cluster
BULLISH ★ 6/10
$0.7630 $0.7900▲ +3.54%▼ −8.84%$0.5180 (−32.11%)
Mar 20, 2026
31w ago
EFFECT
NEUTRAL ★ 4/10
$0.7620 $0.6990▼ −8.27%▼ −22.69%$0.5180 (−32.02%)
Showing 10 of 12

US Market Status

Market Closed — Opens in 21m

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Report published Aug 28, 2026