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Institutional Cluster

AMPH

Amphastar Pharmaceuticals, Inc.
MIXED
Impact 4/10
Horizonweeks Processed2mo ago
Institutional cluster: 12 buyers, 8 sellers (mixed)
Actionable Insight ◆ Mixed

The heavy selling by two large asset managers (Boston Trust Walden and TD Asset Management) in the same quarter is notable, but the simultaneous accumulation by active quant and asset manager funds (D.E. Shaw, Jane Street, Goldman Sachs) creates a mixed signal without insider confirmation. Monitor for any upcoming 10-Q or 8-K filing that could explain the divergence.

DirectionMixed
Confidencemedium
Horizonweeks
Latest settled — T+20d
AMPH ▲ +13.33% at T+20d
NEUTRAL call +13.33% · α vs SPY +13.86% · entry $21.60 → $24.48
Next anchor: T+60d in 21d
Latest observation: T+44 +13.61% FF3 residual α
Entry = T+0 close
Aug 21, 2026
via day close
T+1d
-0.37%
call -0.37% · α -0.08%
$21.52
settled 2mo ago
T+5d
+1.90%
call +1.90% · α +1.42%
$22.01
settled 8w ago
T+20d
+13.33%
call +13.33% · α +13.86%
$24.48
settled 5w ago
T+60d
Pending
in 21d

Executive Summary

Institutional cluster for AMPH shows mixed conviction in Q2 2026: 12 buyers accumulated $13.1M in new positions, led by Goldman Sachs (+$3.7M), D.E. Shaw (+$4.9M), and Jane Street (+$1.8M), while 8 sellers liquidated $59.1M, including full exits by Boston Trust Walden ($18.5M) and TD Asset Management ($30.2M). The massive selling by two major asset managers outweighs the buying by active quant and asset manager funds, but the signals net to mixed as buyers include well-known active managers with potential alpha.

Key Financial Metrics

Direction
distributing
Buy Value
$37.3M
Sell Value
$59.1M
Net Flow
-$46.0M

Institutional Positions

Net institutional flow: -$46.0M

▲ Buyers (12)

InstitutionActionChangePosition ValueValue Δ
D.E. ShawADD+33.3%$17.9M$4.9M
Goldman SachsADD+53.4%$10.2M$3.7M
Jane Street GroupADD+93.3%$3.6M$1.8M

▼ Sellers (8)

InstitutionActionChangePrev ValueValue Δ
TD Asset ManagementEXIT-100%$30.2M-$30.2M
Boston Trust WaldenEXIT-100%$18.5M-$18.5M
MillenniumNEAR_EXIT-91.4%$7.3M-$6.6M

Key Facts

  • 12 institutional buyers added $13.1M in net new positions, led by D.E. Shaw (+$4.9M), Goldman Sachs (+$3.7M), and Jane Street (+$1.8M)
  • 8 institutional sellers reduced holdings by $59.1M, with two full exits: TD Asset Management ($30.2M) and Boston Trust Walden ($18.5M)
  • Sellers include 2 quant funds (Citadel near-exit, Millennium near-exit -91.4%) and 2 mega-passive managers
  • Active managers dominate the buying side (D.E. Shaw, Jane Street, Susquehanna, Citigroup, Russell Investments), but passive asset managers (Goldman Sachs, Wells Fargo) also added modestly
  • No insider open-market buying to corroborate the institutional accumulation
  • 13F data is as of June 30, 2026 with a 45-day lag; positions may have changed since quarter-end

Financial Impact

Net institutional activity: $13.1M in buying vs $59.1M in selling – net selling of approximately $46.0M. The selling is driven primarily by two full-exit funds ($48.7M) that were top-10 holders, representing a significant reduction in institutional ownership

institutional ownershipfloat percentage

Risk Factors

  • 13F data is 45+ days stale; cluster may have been partially or fully unwound
  • Full exits by two top-10 holders ($48.7M combined) suggest fundamental thesis concerns
  • No insider buying to corroborate institutional accumulation — signals are divergent per 13F × Form 4 confluence score
  • 13F does not capture short positions or options overlays, which could mask the true institutional thesis

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
0% bullish (12 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-AMPH-2026-Q2
8 reports for AMPH
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for AMPH — sortable, filterable
TypeNow
Sep 23, 2026
4w ago
Insider Cluster
NEUTRAL ★ 3/10
$26.27awaiting T+60——
Sep 21, 2026
4w ago
144
NEUTRAL ★ 2/10
$24.32awaiting T+60——
Aug 21, 2026
9w ago
Institutional Cluster
MIXED ★ 4/10
$21.60awaiting T+60——
Aug 12, 2026
10w ago
Insider Cluster
NEUTRAL ★ 2/10
$20.18awaiting T+60——
Aug 11, 2026
10w ago
144
NEUTRAL ★ 2/10
$20.31awaiting T+60——
Jul 13, 2026
15w ago
8-K
NEUTRAL ★ 2/10
$19.29 $25.91▲ +34.32%▲ +30.32%—
Jul 7, 2026
15w ago
8-K
BEARISH ★ 6/10
$18.88 $25.35▼ −34.27%▼ −31.78%—
Apr 13, 2026
27w ago
DEFA14A
NEUTRAL ★ 3/10
$21.38 $19.02▼ −11.04%▼ −19.56%—
Showing 8 of 8

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Report published Aug 21, 2026