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Insider Cluster (5 insiders) ·Filed Feb 23, 2026

AMLX

Amylyx Pharmaceuticals, Inc.
BEARISH
Impact 7/10
Horizondays Processed7mo ago
Insider cluster: 2 insiders, $472K total
Actionable Insight ▼ Bearish

Traders should monitor for potential downward pressure on AMLX shares and watch for any upcoming filings (e.g., 10-Q, press releases) that may explain this coordinated exit. Absent positive news, this pattern may signal waning confidence in near-term prospects.

DirectionBearish
Confidencehigh
Horizondays
Final — all horizons settled through T+60d
AMLX ▼ -7.48% at T+60d
SHORT call ✓ call won +7.48% · α vs SPY +15.73% · entry $13.90 → $12.86
Entry = T+0 close
Feb 22, 2026
via day close
T+1d
+5.83%
call -5.83% · α -5.09%
$14.71
settled 8mo ago
T+5d
+10.07%
call -10.07% · α -9.45%
$15.30
settled 8mo ago
T+20d
-2.66%
call +2.66% · α -1.28%
$13.53
settled 7mo ago
T+60d
-7.48%
call +7.48% · α +15.73%
$12.86
settled 5mo ago

Price Chart

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Executive Summary

Five senior executives at Amylyx Pharmaceuticals, including both Co-CEOs, the CFO, CMO, and Chief Legal Officer, collectively sold over $1.16 million in shares in a single day. This represents a coordinated open-market sell-off by top leadership, with no offsetting purchases.

Key Financial Metrics

Direction
selling
Total Value
$1.2M
Insiders
5

Key Facts

  • All five transactions were open-market sales (Form 4 code 'S') executed on the same day (2026-03-02).
  • Total value of sales: $1,156,315.69 (approximately $1.16M).
  • Sellers include both Co-CEOs (Klee and Cohen), CFO (Frates), CMO (Bedrosian), and Chief Legal Officer (Mazzariello).
  • This cluster represents ~0.077% of the company's $1.5B market cap — modest in size but highly significant due to concentration among C-suite executives.
  • No insider purchases or non-cash transactions (e.g., A, F, M) were reported in this cluster.

Financial Impact

$1.16 million in net insider selling by top executives

insider sentimentinvestor confidence

Risk Factors

  • Insiders may be diversifying after a vesting event, not necessarily due to negative outlook.
  • No direct link to specific adverse business developments in this filing — the concern is behavioral, not fundamental.

Market Snapshot

Exchange
Nasdaq

Investment Themes

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CONTEXT: Insider Cluster Data (5 trades, 7d window)cluster-AMLX-1772658066529
10 reports for AMLX
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for AMLX — sortable, filterable
TypeNow
Oct 5, 2026
21d ago
144
NEUTRAL ★ 3/10
$28.04awaiting T+20—$27.09 (−3.39%)
Sep 14, 2026
6w ago
Insider Cluster
MIXED ★ 4/10
$33.15 $26.85▼ −19.00%▼ −21.73%$27.09 (−18.28%)
Sep 11, 2026
6w ago
144
NEUTRAL ★ 2/10
$33.64 $27.48▼ −18.31%▼ −20.57%$27.09 (−19.47%)
Aug 18, 2026
9w ago
8-K
BULLISH ★ 7/10
$35.11 $33.05▼ −5.87%▼ −4.88%$27.09 (−22.84%)
Aug 15, 2026
10w ago
Institutional Cluster
BULLISH ★ 6/10
$21.43 $33.15▲ +54.69%▲ +56.67%$27.09 (+26.41%)
Aug 6, 2026
11w ago
8-K
NEUTRAL ★ 5/10
$24.19 $33.96▲ +40.39%▲ +39.79%$27.09 (+11.99%)
Jun 11, 2026
19w ago
Institutional Cluster
NEUTRAL ★ 3/10
$13.91 $18.38▲ +32.14%▲ +30.24%$27.09 (+94.75%)
Apr 23, 2026
26w ago
DEFA14A
NEUTRAL ★ 3/10
$17.32 $13.61▼ −21.42%▼ −26.05%$27.09 (+56.41%)
Mar 2, 2026
34w ago
Insider Cluster
NEUTRAL ★ 3/10
$15.30 $12.76▼ −16.60%▼ −8.66%$27.09 (+77.06%)
Feb 23, 2026
35w ago
Insider Cluster
BEARISH ★ 7/10
$13.90 $13.53▲ +2.66%▼ −1.28%$27.09 (−94.89%)
Showing 10 of 10

US Market Status

Market Closed — Opens Tue (16h 35m)

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Report published Mar 4, 2026