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Institutional Cluster

ALXO

ALX ONCOLOGY HOLDINGS INC
BEARISH
Impact 5/10
Horizonweeks Processed4mo ago
Institutional cluster: 6 buyers, 4 sellers (mixed)
Actionable Insight ▼ Bearish

The heavy selling by Marshall Wace and near-exits by three other institutions suggest a loss of confidence. Monitor for upcoming earnings or pipeline catalysts that could reverse sentiment. The small buying by D.E. Shaw and Verition may be speculative bets on a binary event, not a conviction re-rating.

DirectionBearish
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d
ALXO ▲ +26.58% at T+60d
SHORT call ✗ call lost -26.58% · α vs SPY -23.32% · entry $1.58 → $2.00
Entry = T+0 close
Jun 12, 2026
via day close
T+1d
0.00%
call 0.00% · α +1.76%
$1.58
settled 4mo ago
T+5d
-3.16%
call +3.16% · α +3.84%
$1.53
settled 4mo ago
T+20d
+34.49%
call -34.49% · α -32.71%
$2.13
settled 4mo ago
T+60d
+26.58%
call -26.58% · α -23.32%
$2.00
settled 7w ago

Executive Summary

A mixed institutional cluster in ALXO for Q3 2024 shows 6 buyers (net +$124K) and 4 sellers (net -$3.74M), dominated by a massive trim from Marshall Wace (-$3.54M, -74.8% of its position). While D.E. Shaw (+$414K, +1433%) and Verition (+$46K, +308%) doubled down, the aggregate selling pressure far outweighs buying, suggesting institutional de-risking ahead of a catalyst or deteriorating fundamentals.

Key Financial Metrics

Direction
distributing
Buy Value
$1.4M
Sell Value
$3.7M
Net Flow
-$3.6M

Institutional Positions

Net institutional flow: -$3.6M

▲ Buyers (6)

InstitutionActionChangePosition ValueValue Δ
D.E. ShawDOUBLED+1433.2%$529.0K$414.0K
Verition Fund ManagementDOUBLED+308.4%$242.0K$46.0K
Walleye CapitalDOUBLED+110.3%$420.0K-$241.7K

▼ Sellers (4)

InstitutionActionChangePrev ValueValue Δ
Marshall WaceTRIM-74.8%$3.8M-$3.5M
Legal & General GroupNEAR_EXIT-85.1%$156.0K-$149.1K
Zurcher KantonalbankNEAR_EXIT-80.9%$39.0K-$37.0K

Key Facts

  • 6 buyers added $124K net; 4 sellers reduced $3.74M net — net selling of ~$3.62M
  • Marshall Wace cut 74.8% of its position, selling $3.54M worth of shares
  • D.E. Shaw increased its stake by 1,433% (+$414K), the largest buyer by value
  • Three sellers (Russell, Zurcher Kantonalbank, Legal & General) nearly exited entirely
  • All funds are categorized as asset managers or quant — no activist or family office presence

Financial Impact

Net institutional selling of approximately $3.62M in Q3 2024, with total selling value of $3.74M versus buying of $124K

institutional ownershipfloat

Risk Factors

  • Marshall Wace's large trim could signal negative non-public information
  • All sellers are asset managers, not distressed or forced sellers — likely deliberate thesis abandonment

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
85% bullish (13 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-ALXO-2024-Q3
15 reports for ALXO
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for ALXO — sortable, filterable
TypeNow
Oct 16, 2026
9d ago
SC 13D/A
NEUTRAL ★ 4/10
$1.14 $1.13▼ −0.88%▼ −0.73%—
Oct 15, 2026
11d ago
8-K
MIXED ★ 6/10
$1.06 $1.17▲ +10.38%▲ +10.81%—
Sep 28, 2026
28d ago
Press Release
MIXED ★ 5/10
$1.39 $1.21▼ −12.95%▼ −14.15%—
Aug 15, 2026
10w ago
Institutional Cluster
NEUTRAL ★ 4/10
$1.97 $1.99▲ +1.02%▲ +2.21%—
Aug 6, 2026
11w ago
8-K
NEUTRAL ★ 4/10
$2.11 $1.94▼ −8.06%▼ −9.27%—
Jun 30, 2026
16w ago
8-K
NEUTRAL ★ 3/10
$2.06 $2.36▲ +14.56%▲ +14.30%—
Jun 26, 2026
17w ago
8-K
NEUTRAL ★ 5/10
$2.20 $2.19▼ −0.45%▼ −1.84%—
Jun 12, 2026
19w ago
Institutional Cluster
BEARISH ★ 5/10
$1.58 $1.53▲ +3.16%▲ +3.84%—
May 8, 2026
24w ago
8-K
NEUTRAL ★ 5/10
$2.08 $2.04▼ −1.92%▼ −3.39%—
May 8, 2026
24w ago
Press Release
BEARISH ★ 6/10
$2.08 $2.04▲ +1.92%▲ +3.39%—
Showing 10 of 15

US Market Status

Market Closed — Opens Wed (12h 36m)

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Report published Jun 12, 2026