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SC 13D ·Filed Oct 2, 2026

ADRX

ADARx Pharmaceuticals, Inc.
NEUTRAL
Impact 5/10
Horizonweeks Processed24d 21h ago SEC0000947871-26-000917
Activist investor acquires 5%+ stake
Actionable Insight • Neutral

OrbiMed's 14% stake and two board seats provide significant influence, but the filing explicitly disclaims control intent and enumerates no specific proposals. Monitor for any future 13D amendments signaling a shift toward activist demands, particularly around strategic alternatives or operational changes, as the lock-up expiration (late March 2027) approaches.

DirectionNeutral
Confidencehigh
Horizonweeks
Latest settled — T+5d
ADRX ▼ -5.67% at T+5d
NEUTRAL call -5.67% · α vs SPY -6.09% · entry $19.05 → $17.97
Next anchor: T+20d in 3d
Entry = T+0 close
Oct 2, 2026
via day close
T+1d
-2.47%
call -2.47% · α -3.02%
$18.58
settled 22d ago
T+5d
-5.67%
call -5.67% · α -6.09%
$17.97
settled 18d ago
T+20d
Pending
in 3d
T+60d
Pending
in 2mo

Price Chart

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Executive Summary

OrbiMed Advisors LLC and affiliated entities filed a Schedule 13D disclosing beneficial ownership of 14,913,764 shares of ADARx Pharmaceuticals, Inc., representing approximately 14.0% of the outstanding common stock. The stake was acquired through pre-IPO preferred stock conversions and IPO participation, and the filing states the investment was made without intent to control the company. Two OrbiMed designees (Carl L. Gordon and Erez Chimovits) serve on ADARx's board, giving OrbiMed board-level influence.

Key Financial Metrics

Stake
14%
Investor
OrbiMed Advisors LLC

Key Facts

  • OrbiMed Advisors LLC and affiliates collectively own 14,913,764 shares, or ~14.0% of ADARx common stock.
  • Stake comprises 14,325,529 shares (13.4%) held by OrbiMed Private Investments VII, LP; 9,292,025 shares (8.7%) by OrbiMed Israel Partners II, LP; and 588,235 shares (0.6%) by OrbiMed Genesis Master Fund, LP.
  • Shares were acquired through conversion of Series A, B, B-1, and C Preferred Stock upon IPO, plus IPO purchases at $17.00 per share.
  • Carl L. Gordon and Erez Chimovits, both OrbiMed affiliates, serve on ADARx's Board of Directors.
  • The filing states no plans for control, extraordinary transactions, board changes, or other enumerated actions.
  • Lock-up agreements restrict sales by OPI VII, OIP II, Gordon, and Chimovits for 180 days after the IPO prospectus date (September 28, 2026).
  • Registration rights (demand, piggyback, S-3) are held by the reporting persons under the Third Amended and Restated Investors' Rights Agreement.

Financial Impact

OrbiMed's aggregate stake value based on IPO price of $17.00/share is approximately $253.5 million (14,913,764 shares × $17.00).

ownership concentrationboard composition

Risk Factors

  • OrbiMed could seek board changes or strategic review in future amendments despite current passive language.
  • Lock-up expiration in ~6 months may lead to secondary sales, creating overhang.
  • Registration rights could facilitate future share sales by OrbiMed, potentially pressuring the stock.

Investment Themes

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13D Filing (Primary)0000947871-26-000917
Document: 0000947871-26-000917-index-headers.html0000947871-26-000917
Document: 0000947871-26-000917-index.html0000947871-26-000917
Document: 0000947871-26-000917.txt0000947871-26-000917
16 reports for ADRX
Performance horizon
67% Hit rate @ T+1 4 of 6 directional calls Went positive at some point 4 of 6 best @ T+1▲ +4.38%Oct 1, 2026
Filters
Rows
Reports for ADRX — sortable, filterable
TypeNow
Oct 16, 2026
10d ago
SC 13G
NEUTRAL ★ 3/10
$17.63 $17.68▲ +0.28%▼ −0.05%$18.25 (+3.52%)
Oct 5, 2026
21d ago
SC 13D
NEUTRAL ★ 5/10
$18.58 $17.33▼ −6.73%▼ −6.49%$18.25 (−1.78%)
Oct 2, 2026
24d ago
SC 13D
NEUTRAL ★ 5/10
$19.05 $18.58▼ −2.47%▼ −3.02%$18.25 (−4.20%)
Oct 1, 2026
25d ago
Press Release
BULLISH ★ 7/10
$18.25 $19.05▲ +4.38%▲ +3.71%$18.25 (0.00%)
Oct 1, 2026
25d ago
SC 13G
NEUTRAL ★ 3/10
$18.25 $19.05▲ +4.38%▲ +3.71%$18.25 (0.00%)
Sep 30, 2026
26d ago
Insider Cluster
BULLISH ★ 7/10
$19.54 $18.25▼ −6.60%▼ −7.34%$18.25 (−6.60%)
Sep 29, 2026
27d ago
Insider Cluster
BULLISH ★ 6/10
$19.94 $19.54▼ −2.01%▼ −2.18%$18.25 (−8.48%)
Sep 25, 2026
4w ago
424B4
BULLISH ★ 7/10
$20.09 $20.64▲ +2.71%▲ +2.90%$18.25 (−9.16%)
Sep 25, 2026
4w ago
EFFECT
BULLISH ★ 8/10
$19.35 $20.09▲ +3.82%▲ +4.57%$18.25 (−5.68%)
Sep 24, 2026
4w ago
Press Release
BULLISH ★ 7/10
$19.35 $20.09▲ +3.82%▲ +4.57%$18.25 (−5.68%)
Showing 10 of 16

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Report published Oct 2, 2026