Nasdaq· Pharmaceutical Preparations· Inc. VA· CIK 0001104506

INSM

INSMED Inc
$109.05 ▲ +0.42%
Prev close $108.59
Market cap$24.9B
ConsensusStrong Buy
12-mo target$197.74 (+80.7%)
▲ Bullish
Analyst conviction 10/10
Insider Selling Cluster (2 insiders)High Impact Filing (8/10)37 New Institutional Positions13 Institutional Exits Biotech & Drug Discovery
Snapshot
The big-picture read on INSM right now — valuation, ownership and activity at a glance.
Market Cap
$24.9B
Cap Size
Large Cap
Analyst Consensus
Strong Buy (97%)
Inst. Holders
50 funds
Inst. Value
$17.8B
Inst. Activity
37 buys / 13 sells
Insider Activity
$0.00 buy / $53.5M sell
Insider Net $
-$53.5M
Social Sentiment
75° Bullish
SEC Reports
18
Congressional
1 trades
Price chart 30d -13.9%
Daily candles (open–high–low–close) with volume. Green = up day, red = down day.
Vol
Recent activity
The latest filings, insider trades, analyst actions, press and options flow — newest first.
Oct 2, 2026 clinical_trial_readout
T-90d Trial Readout: Treprostinil Palmitil (Phase 3)
Trial: An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial H
Sep 9, 2026 Insider
Brennan David R sold 25,000 shares
Director @ $124.00 ($3.1M)
Aug 20, 2026 SEC
Two Insmed insiders sold a total of $32.6M in stock over the past week, including COO Roger Adsett's $31.96M sale and Di
CLUSTER — Impact 4/10
Aug 17, 2026 Insider
SHAROKY MELVIN MD sold 5,000 shares
Director @ $127.53 ($637.6K)
Aug 12, 2026 SEC
Insmed's COO and CMO sold a combined $33.1M in stock immediately following a blockbuster Q2 earnings beat (revenue $425.
CLUSTER — Impact 4/10
Aug 10, 2026 Insider
Adsett Roger acquired via exercise 76,600 shares
Chief Operating Officer @ $17.16 ($1.3M)
Jul 21, 2026 SEC
BMO Capital initiates INSM at Outperform — PT $192 (+78.6%)
ANALYST-UPGRADE — Impact 4/10
Jun 30, 2026 Inst.
JPMORGAN CHASE & CO — TRIM
10,428,170 shares ($1.1B)
Analyst ratings buy % +5.4%
How Wall Street rates the stock today, and the latest firm-by-firm actions.
Strong Buy 97% rate it Buy or better · 30 analysts
Strong Buy 9 30% Buy 20 67% Hold 1 3% Sell 0 0% Strong Sell 0 0%
Recent analyst actions
DateFirmActionRatingFirm rating
Sep 30, 2026BarclaysMAINTAINOverweight 54%
Sep 15, 2026Roth CapitalREITERATEBuy 56%
Aug 10, 2026JP MorganMAINTAINOverweight 55%
Aug 10, 2026Truist SecuritiesREITERATEBuy 55%
Aug 7, 2026GuggenheimMAINTAINBuy 52%
Aug 7, 2026Wells FargoMAINTAINOverweight 54%
Aug 7, 2026Evercore ISI GroupMAINTAINOutperform 59%
Jul 21, 2026BMO CapitalINITIATEOutperform 53%
Jul 15, 2026Wells FargoMAINTAINOverweight 54%
Jul 10, 2026GuggenheimREITERATEBuy 52%
Monthly consensus history
PeriodStr. BuyBuyHoldSellStr. SellBuy %Distribution
Sep 1, 202692010097%
Aug 1, 202692010097%
Jul 1, 202691910097%
Jun 1, 202691910097%
May 1, 202691810096%
Apr 1, 202691610096%
Mar 1, 202691520092%
Feb 1, 202691620093%
Price targets
Where 23 covering analysts think INSM trades over the next 12 months.
$197.74 +80.7% upside Strong Buy
Current$109.45 Low$169.00 Median$195.00 High$243.00 23 analysts
$169.00$243.00
Analyst rating Strong Buy· 1.2/5 as of Oct 2, 2026
Social media sentiment mood -16.4%
Retail-investor mood aggregated across social media. 0° = very bearish, 100° = very bullish.
75°
Bullish
BearishNeutralBullish
8 mentions 6 bullish 0 bearish 2 neutral
Recent posts
Reports & filings
AI-scored summaries of recent SEC filings and press releases, with sentiment and impact.
18 SEC filing reports analyzed · 4 bullish, 3 bearish, 0 mixed, 11 neutral · avg impact 4.2/10.
Upcoming & catalyst events
Scheduled dates plus disclosed catalysts — earnings, dividends, enforcement, FDA and clinical-trial events. Colored dot = impact.
Oct 2, 2026
Clinical Trial
An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)
Phase Phase 3 — ACTIVE_NOT_RECRUITING
Oct 2, 2026
clinical_trial_readout
T-90d Trial Readout: Treprostinil Palmitil (Phase 3)
Trial: An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH) Sponsor: Insmed Incorporated Pha
Sep 30, 2026
Clinical Trial
A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
Phase Phase 2 — COMPLETED
Sep 21, 2026
short_volume
Short Volume: INSM — 60.8% short (0.5M / 0.9M)
Short: 544,852 | Exempt: 0 | TRF Vol: 896,382 | Short Ratio: 60.8% | Off-exchange volume (dark pool + OTC)
Sep 18, 2026
short_volume
Short Volume: INSM — 69.5% short (0.7M / 1.1M)
Short: 748,938 | Exempt: 0 | TRF Vol: 1,076,883 | Short Ratio: 69.5% | Off-exchange volume (dark pool + OTC)
Earnings estimates
Forecast earnings per share and revenue by period — and whether estimates are rising.
PeriodEPS Est.RangeGrowth30d RevUp/DnRevenue#
Current Q$-0.36$-0.90–$0.0479.2%-1.0%12↑ 1↓$0.5B17
Next Q$-0.30$-1.12–$0.3580.6%+2.1%10↑ 2↓$0.6B17
Current FY$-1.54$-2.65–$-0.4375.9%+0.6%15↑ 0↓$1.8B18
Next FY$0.77$-0.91–$2.91150.2%-3.4%13↑ 3↓$2.9B18
Current-quarter EPS estimate — revision history
WhenEPS estimateChange vs now
Current$-0.365—
7d ago$-0.359-0.006
30d ago$-0.361-0.004
60d ago$-0.604+0.239
90d ago$-0.610+0.246
Institutional ownership
Which big funds own INSM (from quarterly 13F filings) and who is adding or trimming.
50 institutional holders with $17.8B total value (166,996,798 shares) as of 2026-Q2. Top holders: FMR, BlackRock,, VANGUARD. Net buying activity: 37 institutions added/increased vs 13 reduced.
Top holders — 2026-Q2
FundSharesValue% TrackedLast move
FMR LLC16,143,583$1.7B9.7%—
BlackRock, Inc.15,807,984$1.7B9.5%—
VANGUARD PORTFOLIO MANAGEMENT LLC10,407,962$1.1B6.2%—
JPMORGAN CHASE & CO10,428,170$1.1B6.1%TRIM -56.8%
VANGUARD CAPITAL MANAGEMENT LLC9,790,865$1.0B5.9%—
BAKER BROS. ADVISORS LP8,796,111$937.8M5.3%—
Capital International Investors8,238,124$878.3M4.9%ADD +47.2%
AMERIPRISE FINANCIAL INC6,179,571$658.9M3.7%DOUBLED +102.1%
Orbis Allan Gray Ltd6,076,487$647.9M3.6%DOUBLED +224.5%
STATE STREET CORP6,052,174$645.3M3.6%—
Recent position changes
FundActionPrevCurrentChangeValue
JPMORGAN CHASE & COTRIM24,150,49910,428,170-56.8%$1.1B
Capital International InvestorsADD5,595,1948,238,124+47.2%$878.3M
AMERIPRISE FINANCIAL INCDOUBLED3,057,7186,179,571+102.1%$658.9M
Orbis Allan Gray LtdDOUBLED1,872,8246,076,487+224.5%$647.9M
NORGES BANKNEW—3,377,641—$360.1M
UBS Group AGADD1,737,4812,584,446+48.7%$275.6M
MAVERICK CAPITAL LTDNEW—2,150,762—$229.3M
MILLENNIUM MANAGEMENT LLCADD1,157,7862,048,005+76.9%$218.4M
Qube Research & Technologies LtdDOUBLED148,5151,682,334+1032.8%$179.4M
GOLDMAN SACHS GROUP INCADD942,6461,409,885+49.6%$150.3M
Insider activity
Buying and selling by company executives and directors (SEC Form 4).
8 insiders, 50 transactions. Net -$53.5M — $0.00 bought, $53.5M sold.
DateInsiderTitleTypeSharesPriceValue
Sep 9, 2026Brennan David RDirectorSELL25,000$124.00$3.1M
Aug 17, 2026SHAROKY MELVIN MDDirectorSELL5,000$127.53$637.6K
Aug 10, 2026Adsett RogerChief Operating OfficerEXERCISE76,600$17.16$1.3M
Aug 10, 2026Adsett RogerChief Operating OfficerEXERCISE80,970$30.46$2.5M
Aug 10, 2026Adsett RogerChief Operating OfficerSELL239,850$133.27$32.0M
Aug 10, 2026Adsett RogerChief Operating OfficerEXERCISE82,280$13.67$1.1M
Aug 6, 2026Flammer Martina M.D.Chief Medical OfficerSELL8,895$127.00$1.1M
Aug 6, 2026Flammer Martina M.D.Chief Medical OfficerEXERCISE18,278$18.95$346.4K
Aug 6, 2026Flammer Martina M.D.Chief Medical OfficerSELL18,278$129.40$2.4M
Aug 6, 2026Flammer Martina M.D.Chief Medical OfficerEXERCISE8,895$25.83$229.8K
Congressional trades
INSM trades disclosed by members of Congress, with disclosure delay.
1 members · 0 buys / 1 sells
DateMemberPartyChamberTypeAmountAssetDisclosed
Jun 10, 2026Josh GottheimerDHOUSESELL$1,001 - $15,000INSMED INCJul 8, 2026(29d)
Short interest & halts
FINRA semi-monthly short positions, Reg SHO threshold status, and recent trading halts for INSM.
Shares short
10,802,070
Settlement Sep 15, 2026
Change vs prior
-5.6%
Semi-monthly cycle
Days to cover
5.3
At avg daily volume
Of shares outstanding
≈5.0%
Estimate — not % of float
All INSM filing & press-release reports (18)