Nasdaq· Pharmaceutical Preparations· Inc. U0· CIK 0001631574

WVE

Wave Life Sciences, Inc.
$3.91 ▲ +0.90%
Prev close $3.88
Market cap$717.3M
ConsensusStrong Buy
12-mo target$18.06 (+361.2%)
▲ Bullish
Analyst conviction 10/10
Insider Selling Cluster (4 insiders)High Impact Filing (7/10) Biotech & Drug Discovery
Snapshot
The big-picture read on WVE right now — valuation, ownership and activity at a glance.
Market Cap
$717.3M
Cap Size
Small Cap
Analyst Consensus
Strong Buy (95%)
Insider Activity
$54.6M buy / $892.6K sell
Insider Net $
$53.7M
Social Sentiment
53° Neutral
SEC Reports
7
Press Releases
2
Price chart 30d -19.8%
Daily candles (open–high–low–close) with volume. Green = up day, red = down day.
Vol
Recent activity
The latest filings, insider trades, analyst actions, press and options flow — newest first.
Oct 1, 2026 other
Wave Life Sciences Announces FDA Feedback Supports Registrational Pathway for WVE-006 (RNA Editing) in AATD
Following meeting with FDA, Wave plans for a single, two-year registrational trial, with a one-year
Aug 14, 2026 SEC
Three Wave Life Sciences directors sold a total of ~$132K in open-market shares over a one-week window, with the largest
CLUSTER — Impact 3/10
Aug 12, 2026 Insider
Rawcliffe Adrian sold 12,700 shares
Director @ $5.29 ($67.2K)
Aug 11, 2026 Insider
Wagner Heidi L acquired via exercise 7,000 shares
Director @ $5.97 ($41.8K)
Aug 11, 2026 Insider
TAKANASHI KEN sold 3,864 shares
Director @ $6.01 ($23.2K)
May 18, 2026 Press
Wave Life Sciences reported strong updated Phase 1b/2a data for WVE-006 in AATD, showing restoration of wild-type M-AAT
Impact 7/10
Apr 28, 2026 SEC
Wave Life Sciences reported Q1 2026 EPS of -$0.13, beating consensus estimates of -$0.34 by 61.8%, and revenue of $38.2M
8-K — Impact 7/10
Apr 28, 2026 SEC
Wave Life Sciences reported Q1 2026 revenue of $38.2M (vs consensus $7.9M) and EPS of -$0.13 (vs consensus -$0.31), repr
PRESS-RELEASE — Impact 7/10
Analyst ratings buy % +0.0%
How Wall Street rates the stock today, and the latest firm-by-firm actions.
Strong Buy 95% rate it Buy or better · 21 analysts
Strong Buy 7 33% Buy 13 62% Hold 1 5% Sell 0 0% Strong Sell 0 0%
Recent analyst actions
DateFirmActionRatingFirm rating
Oct 1, 2026Ladenburg ThalmannINITIATEBuy 45%
Sep 23, 2026JP MorganDOWNGRADENeutral 55%
Aug 4, 2026MizuhoMAINTAINOutperform 52%
Jul 31, 2026CitigroupMAINTAINBuy 55%
Jul 31, 2026B. Riley SecuritiesMAINTAINBuy 54%
Jul 31, 2026WedbushMAINTAINOutperform 57%
May 20, 2026Wells FargoMAINTAINOverweight 54%
May 19, 2026HC Wainwright & Co.MAINTAINBuy 43%
May 4, 2026CitigroupMAINTAINBuy 55%
Apr 30, 2026Canaccord GenuityMAINTAINBuy 47%
Monthly consensus history
PeriodStr. BuyBuyHoldSellStr. SellBuy %Distribution
Sep 1, 202671310095%
Aug 1, 202661310095%
Jul 1, 202661310095%
Jun 1, 202661310095%
May 1, 202661310095%
Apr 1, 202661310095%
Mar 1, 202661310095%
Feb 1, 202661310095%
Price targets
Where 18 covering analysts think WVE trades over the next 12 months.
$18.06 +361.2% upside Strong Buy
Current$3.92 Low$10.00 Median$14.50 High$42.00 18 analysts
$10.00$42.00
Analyst rating Strong Buy· 1.3/5 as of Oct 2, 2026
Social media sentiment mood +34.0%
Retail-investor mood aggregated across social media. 0° = very bearish, 100° = very bullish.
53°
Neutral
BearishNeutralBullish
11 mentions 4 bullish 3 bearish 4 neutral
Recent posts
Reports & filings
AI-scored summaries of recent SEC filings and press releases, with sentiment and impact.
7 SEC filing reports analyzed · 2 bullish, 0 bearish, 1 mixed, 4 neutral · avg impact 5.3/10.Plus 2 press releases.
Upcoming & catalyst events
Scheduled dates plus disclosed catalysts — earnings, dividends, enforcement, FDA and clinical-trial events. Colored dot = impact.
Oct 1, 2026
other
Wave Life Sciences Announces FDA Feedback Supports Registrational Pathway for WVE-006 (RNA Editing) in AATD
Following meeting with FDA, Wave plans for a single, two-year registrational trial, with a one-year interim analysis for potential accelerated approva
Sep 30, 2026
contract
Wave Life Sciences Announces GSK’s Selection of siRNA program to Transition to GSK for Further Development
Candidate selected by GSK utilizes Wave’s best-in-class SpiNA design siRNA and triggers a milestone payment to Wave; three additional collaboration pr
Sep 25, 2026
short_volume
Short Volume: WVE — 68.2% short (1.2M / 1.8M)
Short: 1,220,785 | Exempt: 9,515 | TRF Vol: 1,791,174 | Short Ratio: 68.2% | Off-exchange volume (dark pool + OTC)
Sep 23, 2026
other
Wave Life Sciences Initiates Phase 2a Combination Trial of WVE-007 (GalNAc-siRNA) with Tirzepatide for Obesity
WVE-007 induces fat loss without muscle loss, with clinical data supporting 1-2x per year dosing; preclinical data demonstrate Wave’s INHBE GalNAc-siR
Sep 23, 2026
short_volume
Short Volume: WVE — 55.9% short (1.1M / 1.9M)
Short: 1,063,569 | Exempt: 179 | TRF Vol: 1,902,566 | Short Ratio: 55.9% | Off-exchange volume (dark pool + OTC)
Earnings estimates
Forecast earnings per share and revenue by period — and whether estimates are rising.
PeriodEPS Est.RangeGrowth30d RevUp/DnRevenue#
Current Q$-0.32$-0.36–$-0.25-0.1%-1.0%0↑ 1↓$0.0B15
Next Q$-0.33$-0.42–$-0.24-9.6%+0.6%0↑ 1↓$0.0B14
Current FY$-1.10$-1.22–$-0.879.0%+0.7%0↑ 3↓$0.1B15
Next FY$-1.16$-1.68–$-0.07-5.1%+2.8%1↑ 2↓$0.0B16
Current-quarter EPS estimate — revision history
WhenEPS estimateChange vs now
Current$-0.320—
7d ago$-0.320-0.001
30d ago$-0.317-0.003
60d ago$-0.323+0.003
90d ago$-0.307-0.014
Insider activity
Buying and selling by company executives and directors (SEC Form 4).
9 insiders, 27 transactions. Net $53.7M — $54.6M bought, $892.6K sold.
DateInsiderTitleTypeSharesPriceValue
Aug 12, 2026Rawcliffe AdrianDirectorSELL12,700$5.29$67.2K
Aug 11, 2026Wagner Heidi LDirectorEXERCISE7,000$5.97$41.8K
Aug 11, 2026TAKANASHI KENDirectorSELL3,864$6.01$23.2K
Aug 11, 2026Wagner Heidi LDirectorSELL7,000$6.01$42.1K
Aug 11, 2026Tan Aik NaDirectorSELL432$6.01$2.6K
Mar 30, 2026RA CAPITAL MANAGEMENT, L.P.DirectorBUY971,091$6.50$6.3M
Mar 27, 2026RA CAPITAL MANAGEMENT, L.P.DirectorBUY2,495,623$6.43$16.0M
Mar 26, 2026RA CAPITAL MANAGEMENT, L.P.DirectorBUY4,954,558$6.06$30.0M
Mar 26, 2026RA CAPITAL MANAGEMENT, L.P.DirectorBUY351,224$6.38$2.2M
Mar 23, 2026TAKANASHI KENDirectorCONVERT3,901,348——
Short interest & halts
FINRA semi-monthly short positions, Reg SHO threshold status, and recent trading halts for WVE.
Shares short
17,637,783
Settlement Sep 15, 2026
Change vs prior
+8.3%
Semi-monthly cycle
Days to cover
5.2
At avg daily volume
Of shares outstanding
≈8.9%
Estimate — not % of float
All WVE filing & press-release reports (9)