Insider Cluster (2 insiders) ·Filed Jun 4, 2026

SMMT

Summit Therapeutics Inc.
BULLISH
Impact 6/10
Horizonweeks Processed4mo ago
Insider cluster: 2 insiders, $1.8M total
Actionable Insight ▲ Bullish

This is the strongest insider signal possible at SMMT — both the Co-CEO and COO/CFO buying aggressively on the same day with their own cash at a ~$11.7B market cap. Given the company's clinical-stage profile and the historical underperformance of prior neutral/bearish calls, this cluster buy suggests the upcoming pipeline catalyst (likely ivonescimab data or regulatory update) is seen internally as highly value-accretive. Traders should monitor for an imminent press release or clinical data readout.

DirectionBullish
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d ⚠ clustered
SMMT ▼ -7.79% at T+60d
LONG call ✗ call lost -7.79% · α vs SPY -11.79% · entry $14.77 → $13.62
Entry anchored
Jun 4, 04:42 PM ET
via exchange tick
T+1d
-4.47%
call -4.47% · α -4.69%
$14.11
settled 4mo ago
T+5d
-5.15%
call -5.15% · α -5.71%
$14.01
settled 4mo ago
T+20d
+7.85%
call +7.85% · α +5.99%
$15.93
settled 3mo ago
T+60d
-7.79%
call -7.79% · α -11.79%
$13.62
settled 5w ago

Price Chart

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Executive Summary

Co-CEO Mahkam Zanganeh and COO/CFO Manmeet Singh collectively purchased $1.82M in open-market shares at ~$14.50 on June 4, 2026. This is a strong cluster of insider buying from the two top executives, representing ~0.016% of the $11.7B market cap — trivial in percentage terms but highly significant as a C-suite conviction signal at an all-time-high-ish valuation for this clinical-stage biotech.

Key Financial Metrics

Direction
buying
Total Value
$1.8M
Insiders
2

Key Facts

  • Co-CEO Mahkam Zanganeh bought 100K shares at $14.60 for $1.46M in an open-market purchase.
  • COO/CFO Manmeet Singh bought 25K shares at $14.46 for $361.5K in an open-market purchase.
  • Total cluster value: $1.82M, all open-market buys — no non-cash or tax-withholding transactions.
  • Both purchases occurred on the same day (June 4, 2026), indicating coordinated or strongly aligned conviction.
  • At $11.7B market cap, the total buy value is only ~0.016% of market cap — trivial by proportionality but amplified by C-suite cluster buy literature.
  • No 10b5-1 pattern or regular-interval sales detected; these are discretionary open-market purchases.
  • Prior reports on SMMT have negative T+20 tracking, but those were neutral/bearish reads; this is the first direct bullish insider buy cluster call.

Financial Impact

$1.82M in insider open-market purchases at ~$14.50/share, representing ~0.016% of market cap — small absolute but rare C-suite cluster buy.

insider ownershipmanagement confidence signal

Risk Factors

  • The buy value is less than 0.02% of market cap — insiders could be attempting to signal confidence ahead of data, not reflecting material private information.
  • Prior SMMT reports have shown poor T+20 tracking for neutral calls; however, this is the first clear bullish buy-cluster read in the history.
  • Clinical-stage binary risk remains high regardless of insider sentiment — actual trial results determine the stock, not insider positioning.
  • The stock trades at ~$14.50 near or above recent levels; insiders buying at elevated prices is unusual and could be misinterpreted as anchoring bias.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
67% bullish (24 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-SMMT-1780609536117
16 reports for SMMT
Performance horizon
70% Hit rate 7 of 10 directional calls best @ T+60▲ +23.34%Jun 12, 2026
Filters
Rows
Reports for SMMT — sortable, filterable
TypeNow
Sep 15, 2026
17d ago
8-K
BULLISH ★ 7/10
$17.40 $17.85▲ +2.59%▲ +1.77%$16.75 (−3.71%)
Sep 14, 2026
18d ago
8-K
BULLISH ★ 7/10
$18.42 $16.90▼ −8.25%▼ −8.36%$16.75 (−9.04%)
Sep 3, 2026
29d ago
8-K
BULLISH ★ 6/10
$17.13 $17.55▲ +2.45%▲ +3.60%$16.75 (−2.19%)
Aug 26, 2026
5w ago
8-K
BULLISH ★ 7/10
$14.23 $14.60▲ +2.60%▲ +2.72%$16.75 (+17.74%)
Aug 5, 2026
8w ago
8-K
BULLISH ★ 6/10
$13.53 $15.10▲ +11.60%▲ +11.25%$16.75 (+23.84%)
Jul 22, 2026
10w ago
8-K
BULLISH ★ 7/10
$14.74 $12.80▼ −13.16%▼ −10.76%$16.75 (+13.67%)
Jun 12, 2026
16w ago
Insider Cluster
BULLISH ★ 6/10
$14.01 $13.75▼ −1.86%▼ −2.53%$16.75 (+19.59%)
Jun 12, 2026
16w ago
Institutional Cluster
MIXED ★ 4/10
$14.01 $13.75▼ −1.86%▼ −2.53%$16.75 (+19.59%)
Jun 11, 2026
16w ago
Institutional Cluster
NEUTRAL ★ 3/10
$13.08 $14.07▲ +7.57%▲ +7.14%$16.75 (+28.10%)
Jun 9, 2026
16w ago
S-3ASR
BEARISH ★ 7/10
$13.05 $13.88▼ −6.36%▼ −2.93%$16.75 (−28.39%)
Showing 10 of 16

US Market Status

Market Closed — Opens Mon (37h 48m)

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Report published Jun 4, 2026