Insider Cluster (2 insiders) ·Filed Jun 12, 2026

SMMT

Summit Therapeutics Inc.
BULLISH
Impact 6/10
Horizonweeks Processed3mo ago
Insider cluster: 2 insiders, $100.0M total
Actionable Insight ▲ Bullish

The scale and seniority of this insider buying cluster is a strong signal that management sees material upside from current levels. Traders should watch for near-term clinical data catalysts (ivonescimab trial readouts). However, historical insider cluster calls on SMMT have been negative at T+20, so size positions accordingly and consider a trailing stop.

DirectionBullish
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d ⚠ clustered
SMMT ▲ +23.34% at T+60d
LONG call ✓ call won +23.34% · α vs SPY +20.08% · entry $14.01 → $17.28
Entry anchored
Jun 12, 02:35 PM ET
via exchange tick
T+1d
+0.86%
call +0.86% · α -0.91%
$14.13
settled 4mo ago
T+5d
-1.86%
call -1.86% · α -2.53%
$13.75
settled 3mo ago
T+20d
+8.85%
call +8.85% · α +7.07%
$15.25
settled 3mo ago
T+60d
+23.34%
call +23.34% · α +20.08%
$17.28
settled 23d ago

Price Chart

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Executive Summary

Both co-CEOs of Summit Therapeutics (SMMT) each purchased 3.81M shares open-market on June 12, 2026, at $13.12, aggregating ~$100M. This represents ~0.98% of market cap, one of the largest insider buying clusters by dollar value relative to size in the sector. The unanimous C-suite buying signals extreme management conviction, though prior insider cluster predictions on SMMT have underperformed.

Key Financial Metrics

Direction
buying
Total Value
$100.0M
Insiders
2

Key Facts

  • Co-CEOs Robert W. Duggan and Mahkam Zanganeh each purchased 3,810,000 shares on June 12, 2026.
  • Total insider buying value: ~$99.97M at $13.12/share.
  • Total value equals ~0.98% of SMMT's $10.2B market cap.
  • Both purchases were open-market (code P) — not grants or options exercises.
  • The cluster occurred within a 7-day window with no other insider trades.

Financial Impact

~$100M in insider open-market buying, ~0.98% of market cap.

market capownershipinsider sentiment

Risk Factors

  • Biotech clinical trial risk (ivonescimab data may disappoint).
  • Prior insider cluster reports on SMMT showed negative T+20 returns (avg -19%), suggesting this signal may be less reliable for this ticker.
  • The stock already has a $10.2B market cap — limited upside if market has already priced in optimism.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
67% bullish (24 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-SMMT-1781289346843
16 reports for SMMT
Performance horizon
70% Hit rate 7 of 10 directional calls best @ T+20▲ +20.31%Aug 26, 2026
Filters
Rows
Reports for SMMT — sortable, filterable
TypeNow
Sep 15, 2026
17d ago
8-K
BULLISH ★ 7/10
$17.40 $17.85▲ +2.59%▲ +1.77%$16.75 (−3.71%)
Sep 14, 2026
18d ago
8-K
BULLISH ★ 7/10
$18.42 $16.90▼ −8.25%▼ −8.36%$16.75 (−9.04%)
Sep 3, 2026
29d ago
8-K
BULLISH ★ 6/10
$17.13 $17.55▲ +2.45%▲ +3.60%$16.75 (−2.19%)
Aug 26, 2026
5w ago
8-K
BULLISH ★ 7/10
$14.23 $14.60▲ +2.60%▲ +2.72%$16.75 (+17.74%)
Aug 5, 2026
8w ago
8-K
BULLISH ★ 6/10
$13.53 $15.10▲ +11.60%▲ +11.25%$16.75 (+23.84%)
Jul 22, 2026
10w ago
8-K
BULLISH ★ 7/10
$14.74 $12.80▼ −13.16%▼ −10.76%$16.75 (+13.67%)
Jun 12, 2026
16w ago
Insider Cluster
BULLISH ★ 6/10
$14.01 $13.75▼ −1.86%▼ −2.53%$16.75 (+19.59%)
Jun 12, 2026
16w ago
Institutional Cluster
MIXED ★ 4/10
$14.01 $13.75▼ −1.86%▼ −2.53%$16.75 (+19.59%)
Jun 11, 2026
16w ago
Institutional Cluster
NEUTRAL ★ 3/10
$13.08 $14.07▲ +7.57%▲ +7.14%$16.75 (+28.10%)
Jun 9, 2026
16w ago
S-3ASR
BEARISH ★ 7/10
$13.05 $13.88▼ −6.36%▼ −2.93%$16.75 (−28.39%)
Showing 10 of 16

US Market Status

Market Closed — Opens Mon (37h 46m)

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Report published Jun 12, 2026