Insider Cluster (2 insiders) ·Filed Jul 17, 2026

ONC

BeOne Medicines Ltd.
BEARISH
Impact 5/10
Horizondays Processed2mo ago
Insider cluster: 2 insiders, $1.5M total
Actionable Insight ▼ Bearish

Monitor for any negative corporate developments (e.g., guidance cuts, trial setbacks) that may have prompted the CEO's large-scale selling. The cluster's size and seniority warrant caution; consider reducing exposure or setting tighter stop-losses until next catalyst.

DirectionBearish
Confidencemedium
Horizondays
Latest settled — T+20d
ONC ▲ +11.36% at T+20d
SHORT call ✗ call lost -11.36% · α vs SPY -6.92% · entry $312.02 → $347.48
Next anchor: T+60d in 7d
Latest observation: T+52 -23.33% FF3 residual α
Entry anchored
Jul 16, 03:59 PM ET
via exchange tick
T+1d
-0.46%
call +0.46% · α +0.30%
$310.58
settled 3mo ago
T+5d
+4.73%
call -4.73% · α -5.41%
$326.77
settled 2mo ago
T+20d
+11.36%
call -11.36% · α -6.92%
$347.48
settled 7w ago
T+60d
—
call — · α —
—
in 7d

Price Chart

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Executive Summary

CEO John Oyler sold ~$43.2M in open-market shares on July 16-17 after exercising options, while SVP/General Counsel Lee Chan Henry sold $201K on July 8. Total insider selling over 10 days reached ~$44.6M, representing 0.13% of market cap. The concentrated CEO selling, though modest relative to market cap, is a notable bearish signal given the magnitude and seniority.

Key Financial Metrics

Direction
selling
Total Value
$44.6M
Insiders
2

Key Facts

  • CEO John Oyler sold ~$43.2M in open-market shares on July 16-17, following derivative exercises of ~3M shares at $0 and $119.96.
  • SVP/General Counsel Lee Chan Henry sold $201K on July 8.
  • Total insider selling over the cluster window: ~$44.6M (0.13% of $34.7B market cap).
  • Oyler's sales were part of a pre-arranged plan? No 10b5-1 pattern noted; sales occurred on two consecutive days after option exercises.

Financial Impact

Insider selling of ~$44.6M, or 0.13% of market cap, concentrated in CEO open-market sales.

insider ownershipmarket sentiment

Risk Factors

  • CEO selling may signal management's view that shares are overvalued or that near-term headwinds exist.
  • Further insider selling could follow, amplifying bearish sentiment.
  • Historical calibration shows high-score insider reports on ONC have underperformed, suggesting limited downside from this signal alone.

Market Snapshot

Exchange
OTC
Sector
Pharmaceutical Preparations
Analyst Consensus
92% bullish (12 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-ONC-1784350936113
19 reports for ONC
Performance horizon
50% Hit rate 2 of 4 directional calls best @ T+20▲ +10.46%Aug 5, 2026
Filters
Rows
Reports for ONC — sortable, filterable
TypeNow
Sep 10, 2026
22d ago
Insider Cluster
NEUTRAL ★ 3/10
$346.51 $350.84▲ +1.25%▲ +1.47%$358.07 (+3.34%)
Sep 3, 2026
29d ago
Insider Cluster
NEUTRAL ★ 2/10
$362.68 $346.51▼ −4.46%▼ −3.31%$358.07 (−1.27%)
Aug 26, 2026
5w ago
8-K
NEUTRAL ★ 2/10
$375.80 $361.78▼ −3.73%▼ −3.61%$358.07 (−4.72%)
Aug 14, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$347.48 $374.47▲ +7.77%▲ +9.14%$358.07 (+3.05%)
Aug 12, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$356.01 $369.16▲ +3.69%▲ +5.66%$358.07 (+0.58%)
Aug 10, 2026
7w ago
144
BEARISH ★ 6/10
$359.27 $369.15▼ −2.75%▼ −3.15%$358.07 (+0.33%)
Aug 5, 2026
8w ago
Insider Cluster
NEUTRAL ★ 2/10
$329.80 $356.01▲ +7.95%▲ +6.73%$358.07 (+8.57%)
Aug 5, 2026
8w ago
8-K
BULLISH ★ 7/10
$327.53 $359.05▲ +9.62%▲ +9.27%$358.07 (+9.32%)
Jul 24, 2026
10w ago
Insider Cluster
NEUTRAL ★ 2/10
$325.90 $322.08▼ −1.17%▼ −1.55%$358.07 (+9.87%)
Jul 17, 2026
11w ago
Insider Cluster
BEARISH ★ 5/10
$312.02 $326.77▼ −4.73%▼ −5.41%$358.07 (−14.76%)
Showing 10 of 19

US Market Status

Market Closed — Opens Mon (38h 34m)

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Report published Jul 18, 2026