PRESS-RELEASE ·Filed Apr 28, 2026

NAUT

Nautilus Biotechnology Inc.
NEUTRAL
Impact 4/10
Horizonmonths Processed5mo ago WireGlobeNewswire
Press release: earnings
Actionable Insight • Neutral

The EPS beat and narrowing loss are incremental positives, but with zero revenue and no guidance provided, the stock remains a binary event on commercial launch timing. Monitor for Early Access customer expansions and next-gen assay development milestones as catalysts.

DirectionNeutral
Confidencehigh
Horizonmonths
Final — all horizons settled through T+60d
NAUT ▼ -31.66% at T+60d
NEUTRAL call ✗ call lost -31.66% · α vs SPY -35.65% · entry $2.59 → $1.77
Entry anchored
Apr 27, 03:59 PM ET
via exchange tick
T+1d
-3.47%
call -3.47% · α -3.47%
$2.50
settled 5mo ago
T+5d
+11.58%
call +11.58% · α +9.89%
$2.89
settled 5mo ago
T+20d
-6.18%
call -6.18% · α -11.65%
$2.43
settled 4mo ago
T+60d
-31.66%
call -31.66% · α -35.65%
$1.77
settled 2mo ago

Price Chart

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Executive Summary

Nautilus Biotechnology reported Q1 2026 EPS of -$0.12, beating consensus of -$0.14 by 17.2%, with revenue still at $0 as a pre-commercialization stage company. Operating expenses fell 14% YoY to $16.1M, and net loss narrowed to $14.7M from $16.6M, while cash and investments stood at $143.4M. The beat is modest for a development-stage firm with no revenue, but the narrowing loss and cash runway extension are incremental positives.

Key Financial Metrics

EPS
$-0.12
est $-0.14 · +17.2%
Revenue
$0.00
est $0.00
Rating
in line
Free Cash Flow
-$13.6M

Key Facts

  • Q1 2026 EPS: -$0.12 vs consensus -$0.14 (17.2% beat)
  • Revenue: $0 (pre-commercialization, no consensus revenue estimate)
  • Operating expenses: $16.1M, down 14% YoY from $18.8M
  • Net loss: $14.7M vs $16.6M YoY, narrowing by 11.5%
  • Cash, cash equivalents, and investments: $143.4M as of March 31, 2026
  • Initiated Iterative Mapping Early Access Program with Baylor College of Medicine
  • Appointed Amber Faust as VP of Global Sales from Olink/SomaLogic

Financial Impact

EPS beat of $0.02 vs consensus, net loss improved by $1.9M YoY

epsnet lossoperating expensescash runway

Risk Factors

  • No revenue and pre-commercialization stage — binary outcome on platform launch success
  • Cash burn of ~$13.1M operating cash flow per quarter implies ~11 quarters of runway
  • No guidance provided, limiting forward visibility

Market Snapshot

Exchange
Nasdaq
Sector
Laboratory Analytical Instruments
Analyst Consensus
88% bullish (8 analysts)

Investment Themes

Industrials & Manufacturing

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3282599
4 reports for NAUT
Performance horizon
Filters
Rows
Reports for NAUT — sortable, filterable
TypeNow
Apr 28, 2026
22w ago
Press Release
NEUTRAL ★ 4/10
$2.59 $1.77▼ −31.66%▼ −35.65%$1.86 (−28.38%)
Apr 28, 2026
22w ago
8-K
NEUTRAL ★ 4/10
$2.59 $1.77▼ −31.66%▼ −35.65%$1.86 (−28.38%)
Mar 18, 2026
28w ago
Press Release
MIXED ★ 6/10
$2.74 $2.29▼ −16.61%▼ −28.13%$1.86 (−32.30%)
Feb 26, 2026
31w ago
8-K
NEUTRAL ★ 4/10
$2.42 $2.54▲ +4.96%▼ −2.79%$1.86 (−23.35%)
Showing 4 of 4

US Market Status

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Report published Apr 28, 2026