8-K ·Filed Apr 28, 2026

NAUT

Nautilus Biotechnology, Inc.
NEUTRAL
Impact 4/10
Horizondays Processed5mo ago SEC0001808805-26-000015
8-K Item 2.02: Earnings release
Actionable Insight • Neutral

Nautilus Biotechnology reported Q1 2026 results: net loss of $14.7M improved from $16.6M a year ago, with operating expenses down 14% to $16.1M. The company initiated its Early Access Program with Baylor College of Medicine and appointed a VP of Global Sales, but reiterated no material revenue in 2026 and expects operating expenses to increase 15-20% YoY. Cash burn continues with $143.4M in cash and investments, sufficient through 2027.

DirectionNeutral
Confidencehigh
Horizondays
Final — all horizons settled through T+60d ⚠ clustered
NAUT ▼ -31.66% at T+60d
NEUTRAL call ✗ call lost -31.66% · α vs SPY -35.65% · entry $2.59 → $1.77
Entry anchored
Apr 28, 2026
via day open
T+1d
-3.47%
call -3.47% · α -3.47%
$2.50
settled 5mo ago
T+5d
+10.42%
call +10.42% · α +8.73%
$2.86
settled 5mo ago
T+20d
-1.16%
call -1.16% · α -6.61%
$2.56
settled 4mo ago
T+60d
-31.66%
call -31.66% · α -35.65%
$1.77
settled 2mo ago

Price Chart

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Executive Summary

Nautilus Biotechnology reported Q1 2026 results: net loss of $14.7M improved from $16.6M a year ago, with operating expenses down 14% to $16.1M. The company initiated its Early Access Program with Baylor College of Medicine and appointed a VP of Global Sales, but reiterated no material revenue in 2026 and expects operating expenses to increase 15-20% YoY. Cash burn continues with $143.4M in cash and investments, sufficient through 2027.

Key Facts

  • Net loss of $14.7M in Q1 2026 vs $16.6M in Q1 2025 (improvement of $1.9M)
  • Operating expenses of $16.1M, down 14% from $18.8M a year ago
  • Cash, cash equivalents, and investments of $143.4M as of March 31, 2026
  • First customer (Baylor College of Medicine) in Early Access Program for Tau proteoform assay
  • Appointed Amber Faust as VP of Global Sales from Olink Proteomics and SomaLogic
  • No material revenue expected in 2026 from Early Access Program
  • Operating expenses expected to increase 15-20% YoY in 2026
  • Cash runway sufficient through 2027
  • Investment backlog of $1.8B as of April 23, 2026

Financial Impact

Not specified

Market Snapshot

Exchange
Nasdaq
Sector
Laboratory Analytical Instruments
Analyst Consensus
88% bullish (8 analysts)

Investment Themes

Industrials & Manufacturing

Documents Analyzed

This report is based on 6 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001808805-26-000015
Document: naut-20260428.htm0001808805-26-000015
Document: 0001808805-26-000015-index-headers.html0001808805-26-000015
Document: 0001808805-26-000015-index.html0001808805-26-000015
Document: 0001808805-26-000015.txt0001808805-26-000015
8-K Data (Synthetic)0001808805-26-000015
4 reports for NAUT
Performance horizon
Filters
Rows
Reports for NAUT — sortable, filterable
TypeNow
Apr 28, 2026
22w ago
Press Release
NEUTRAL ★ 4/10
$2.59 $1.77▼ −31.66%▼ −35.65%$1.86 (−28.38%)
Apr 28, 2026
22w ago
8-K
NEUTRAL ★ 4/10
$2.59 $1.77▼ −31.66%▼ −35.65%$1.86 (−28.38%)
Mar 18, 2026
28w ago
Press Release
MIXED ★ 6/10
$2.74 $2.29▼ −16.61%▼ −28.13%$1.86 (−32.30%)
Feb 26, 2026
31w ago
8-K
NEUTRAL ★ 4/10
$2.42 $2.54▲ +4.96%▼ −2.79%$1.86 (−23.35%)
Showing 4 of 4

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