Watch for additional HORIZON data in late 2026/early 2027 and Phase 2 trial initiations for MZE782 in PKU and CKD, which could be catalysts. The recent dilution and cash burn rate warrant caution despite strong cash runway.
Price Chart
Executive Summary
Maze Therapeutics reported Q1 2026 net loss of $24.2M ($0.45/share), missing consensus of $0.43/share by 4.7%, with license revenue of $20M from a Shionogi milestone. Positive Phase 2 HORIZON data for MZE829 in AMKD and a strong cash runway into 2029 offset the miss, but the recent $150M offering adds dilution.
Key Financial Metrics
Key Facts
- Q1 2026 net loss $24.2M ($0.45/share) vs consensus ($0.43)
- License revenue $20.0M from Shionogi milestone (no year-ago revenue)
- Cash, equivalents and marketable securities $362.9M at March 31, 2026
- Positive Phase 2 HORIZON data for MZE829: 35.6% mean uACR reduction in broad AMKD
- April 2026 registered offering raised ~$150M gross proceeds
- Cash runway extended into 2029 including April proceeds and $20M milestone
Financial Impact
Q1 2026 net loss $24.2M ($0.45/share), license revenue $20.0M; cash $362.9M; additional $150M offering and $20M milestone in April 2026
Risk Factors
- Dilution from $150M registered offering completed in April 2026
- Clinical trial risks for MZE829 and MZE782
- No approved products; revenue dependent on milestones and partnerships
Market Snapshot
Investment Themes
Documents Analyzed
This report is based on 1 press release from GlobeNewswire.
| Document | Accession Number |
|---|---|
| PRESS-RELEASE Data (Synthetic) | press-3293352 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
Sep 4, 2026 27d ago | Insider Cluster | $26.37 $24.23 | ▼ −8.12% | ▼ −7.00% | $26.69 (+1.20%) |
Sep 4, 2026 27d ago | Insider Cluster | $26.37 $24.23 | ▼ −8.12% | ▼ −7.00% | $26.69 (+1.20%) |
Sep 3, 2026 29d ago | Insider Cluster | $25.87 $24.60 | ▼ −4.91% | ▼ −3.76% | $26.69 (+3.16%) |
Sep 2, 2026 29d ago | 144 | $25.87 $24.60 | ▼ −4.91% | ▼ −3.76% | $26.69 (+3.16%) |
Sep 1, 2026 4w ago | 144 | $26.72 $24.82 | ▼ −7.11% | ▼ −6.15% | $26.69 (−0.12%) |
Aug 17, 2026 6w ago | 3 | $29.13 $30.42 | ▲ +4.43% | ▲ +4.63% | $26.69 (−8.38%) |
Aug 11, 2026 7w ago | Press Release | $27.53 $29.75 | ▲ +8.06% | ▲ +8.51% | $26.69 (−3.06%) |
Aug 7, 2026 8w ago | Institutional Cluster | $28.65 $27.18 | ▼ −5.13% | ▼ −5.53% | $26.69 (−6.85%) |
Aug 5, 2026 8w ago | Insider Cluster | $27.81 $27.53 | ▼ −1.01% | ▼ −1.36% | $26.69 (−4.04%) |
Jul 2, 2026 13w ago | Insider Cluster | $31.26 $32.42 | ▲ +3.71% | ▲ +2.78% | $26.69 (−14.63%) |
US Market Status
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