Insider Cluster (2 insiders) ·Filed May 18, 2026

MAZE

Maze Therapeutics, Inc.
NEUTRAL
Impact 3/10
Horizonweeks Processed4mo ago
Insider cluster: 2 insiders, $441K total
Actionable Insight • Neutral

This cluster is structurally a post-earnings, post-offering, option-exercise-triggered sale — not a signal of deteriorating fundamentals. The 0.03% of market cap is immaterial. C-suite selling of this magnitude at a pre-revenue biotech is routine window-driven diversification. The stronger signal is the $150M raise and extended runway; monitor the MZE829 pivotal trial readout and MZE782 Phase 2 starts for true catalysts.

DirectionNeutral
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d
MAZE ▲ +13.10% at T+60d
NEUTRAL call ✓ call won +13.10% · α vs SPY +6.81% · entry $24.46 → $27.67
Entry anchored
May 18, 2026
via day open
T+1d
+2.33%
call +2.33% · α +1.29%
$25.03
settled 5mo ago
T+5d
+6.50%
call +6.50% · α +4.20%
$26.05
settled 4mo ago
T+20d
+1.55%
call +1.55% · α +0.57%
$24.84
settled 4mo ago
T+60d
+13.10%
call +13.10% · α +6.81%
$27.67
settled 7w ago

Price Chart

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Executive Summary

CEO Jason Coloma and President/CMO Harold Bernstein sold a combined $441K in open-market shares within days of Maze Therapeutics reporting Q1 2026 earnings and completing a $150M offering. The $441K total ($393K from Bernstein, $47K from Coloma) is 0.03% of the $1.4B market cap — well below any material threshold. Bernstein's sale coincided with a same-day exercise of 15,000 options at $10.42, indicating a standard cashless exercise/cover transaction rather than a discretionary bearish bet. The cluster is routine and driven by post-earnings window opening, not informed selling.

Key Financial Metrics

Direction
selling
Total Value
$440.7K
Insiders
2

Key Facts

  • CEO Coloma sold 1,822 shares at $26.00 for $47,372 on May 15
  • CMO Bernstein sold 15,000 shares at $26.22 for $393,354 on May 14
  • Bernstein simultaneously exercised 30,000 total options (15,000 at $10.42 and 15,000 in a separate non-cash exercise), covering tax obligations
  • Total cluster value of $441K represents 0.03% of Maze's $1.4B market cap
  • Insider cluster came 6 days after Maze reported Q1 2026 earnings with a narrower net loss of $24.2M vs $32.8M YoY
  • Maze completed a $150M registered offering in April 2026 extending cash runway into 2029

Financial Impact

$441K in open-market sales; 0.03% of market cap - trivial

insider holdingsdilution from option exercises

Risk Factors

  • Pre-revenue biotech with reliance on clinical pipeline milestones for equity valuation
  • All past MAZE reports show negative T+20 average alpha (-21.9%), suggesting structural downward drift in this name independent of filing content
  • Post-offering dilution overhang from $150M April raise still being digested

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
92% bullish (12 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-MAZE-1779138486836
19 reports for MAZE
Performance horizon
33% Hit rate 1 of 3 directional calls best @ T+5▲ +5.16%Jun 3, 2026
Filters
Rows
Reports for MAZE — sortable, filterable
TypeNow
Sep 4, 2026
27d ago
Insider Cluster
NEUTRAL ★ 2/10
$26.37 $24.23▼ −8.12%▼ −7.00%$26.69 (+1.20%)
Sep 4, 2026
27d ago
Insider Cluster
NEUTRAL ★ 3/10
$26.37 $24.23▼ −8.12%▼ −7.00%$26.69 (+1.20%)
Sep 3, 2026
29d ago
Insider Cluster
NEUTRAL ★ 2/10
$25.87 $24.60▼ −4.91%▼ −3.76%$26.69 (+3.16%)
Sep 2, 2026
29d ago
144
NEUTRAL ★ 2/10
$25.87 $24.60▼ −4.91%▼ −3.76%$26.69 (+3.16%)
Sep 1, 2026
4w ago
144
NEUTRAL ★ 3/10
$26.72 $24.82▼ −7.11%▼ −6.15%$26.69 (−0.12%)
Aug 17, 2026
6w ago
3
NEUTRAL ★ 1/10
$29.13 $30.42▲ +4.43%▲ +4.63%$26.69 (−8.38%)
Aug 11, 2026
7w ago
Press Release
NEUTRAL ★ 4/10
$27.53 $29.75▲ +8.06%▲ +8.51%$26.69 (−3.06%)
Aug 7, 2026
8w ago
Institutional Cluster
BULLISH ★ 5/10
$28.65 $27.18▼ −5.13%▼ −5.53%$26.69 (−6.85%)
Aug 5, 2026
8w ago
Insider Cluster
NEUTRAL ★ 3/10
$27.81 $27.53▼ −1.01%▼ −1.36%$26.69 (−4.04%)
Jul 2, 2026
13w ago
Insider Cluster
NEUTRAL ★ 3/10
$31.26 $32.42▲ +3.71%▲ +2.78%$26.69 (−14.63%)
Showing 10 of 19

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Report published May 18, 2026