8-K ·Filed Apr 10, 2026

CRNX

Crinetics Pharmaceuticals, Inc.
NEUTRAL
Impact 3/10
Horizonweeks Processed5mo ago SEC0001658247-26-000022
8-K context-dependent: Items 5.02
Actionable Insight • Neutral

Monitor pipeline progress and future R&D leadership appointments. The consulting arrangement suggests a managed transition, but the departure of a key officer warrants attention to potential delays in clinical development programs.

DirectionNeutral
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d
CRNX ▲ +115.96% at T+60d
NEUTRAL call ✓ call won +115.96% · α vs SPY +107.04% · entry $38.66 → $83.49
Entry anchored
Apr 10, 03:59 PM ET
via exchange tick
T+1d
+2.82%
call +2.82% · α +1.61%
$39.75
settled 6mo ago
T+5d
+4.11%
call +4.11% · α +0.82%
$40.25
settled 6mo ago
T+20d
-5.46%
call -5.46% · α -13.19%
$36.55
settled 5mo ago
T+60d
+115.96%
call +115.96% · α +107.04%
$83.49
settled 3mo ago

Price Chart

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Executive Summary

Crinetics Pharmaceuticals announced the departure of Jeff Knight as Chief Development and Operating Officer, effective April 10, 2026. He will transition to a one-year consulting role at $400 per hour, capped at 20 hours per month. His unvested equity will be forfeited, and vested options will remain exercisable for three months post-consulting period.

Key Facts

  • Jeff Knight stepped down as Chief Development and Operating Officer effective April 10, 2026.
  • He will serve as an independent consultant for one year at $400 per hour, up to 20 hours per month.
  • Unvested restricted stock units and stock options were forfeited; vested options remain exercisable for three months after the consulting period ends.
  • The company entered into a general release agreement with Knight as part of the separation.

Financial Impact

Minimal direct financial impact. Consulting fees capped at $96,000 annually (20 hours/month x $400/hour x 12 months). Loss of key R&D leadership may affect pipeline execution.

compensationequityR&D leadership

Risk Factors

  • Potential disruption to R&D strategy and clinical development timelines
  • Loss of institutional knowledge in clinical development

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 5 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001658247-26-000022
Document: crnx-20260410.htm0001658247-26-000022
Document: 0001658247-26-000022-index-headers.html0001658247-26-000022
Document: 0001658247-26-000022-index.html0001658247-26-000022
Document: 0001658247-26-000022.txt0001658247-26-000022
15 reports for CRNX
Performance horizon
78% Hit rate 7 of 9 directional calls best @ T+20▲ +138.24%Jun 14, 2026
Filters
Rows
Reports for CRNX — sortable, filterable
TypeNow
Sep 11, 2026
21d ago
15-12G
BULLISH ★ 9/10
—awaiting T+1——
Sep 1, 2026
4w ago
25-NSE
BULLISH ★ 9/10
$84.95 $84.95· 0.00%▼ −0.44%—
Sep 1, 2026
4w ago
8-K
BULLISH ★ 9/10
$84.95 $84.95· 0.00%▼ −0.44%—
Aug 14, 2026
7w ago
8-K
BULLISH ★ 6/10
$84.70 $84.75▲ +0.06%▲ +0.53%—
Aug 3, 2026
8w ago
Press Release
BULLISH ★ 9/10
$83.86 $84.00▲ +0.17%▲ +0.37%—
Jul 10, 2026
12w ago
DEFA14A
BULLISH ★ 7/10
$83.67 $83.71▲ +0.05%▼ −0.31%—
Jul 10, 2026
12w ago
8-K
BULLISH ★ 6/10
$83.67 $83.71▲ +0.05%▼ −0.31%—
Jun 30, 2026
13w ago
Press Release
NEUTRAL ★ 2/10
$38.68 $42.23▲ +9.18%▲ +9.31%—
Jun 14, 2026
15w ago
Press Release
BULLISH ★ 6/10
$35.12 $35.00▼ −0.34%▲ +0.25%—
Jun 14, 2026
15w ago
Press Release
BULLISH ★ 6/10
$35.12 $35.00▼ −0.34%▲ +0.25%—
Showing 10 of 15

US Market Status

Market Closed — Opens Mon (38h 30m)

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